Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performances.

نویسندگان

  • Jan Drobeniuc
  • Jihong Meng
  • Gábor Reuter
  • Tracy Greene-Montfort
  • Natasha Khudyakova
  • Zoya Dimitrova
  • Saleem Kamili
  • Chong-Gee Teo
چکیده

Six immunoassays for detecting immunoglobulin M antibodies to hepatitis E virus were evaluated. Serum samples representing acute infection by each of the 4 viral genotypes as well as nonacute hepatitis E virus infection constituted the test panels. Diagnostic sensitivities and specificities as well as interassay agreement varied widely. Analytical sensitivity limits also were determined and were found to be particularly disparate.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 51 3  شماره 

صفحات  -

تاریخ انتشار 2010